Crew:
    John W. Young [4], Commander
    Thomas K. Mattingly, II [1], CSM Pilot
    Charles M. Duke, Jr. [1], LM Pilot

Backup Crew:
    Fred W. Haise, Commander
    Stuart A. Roosa, CSM Pilot
    Edgar D. Mitchell, LM Pilot

Launch:
    Pad: 39-A
    Date: 16 April 1972
    Time: 17:54:00 UTC

Lunar Landing:
    Location: Descartes Highlands (Lunar 8.97° S, 15.51° E)
    Touchdown: 21 April  02:23:35 UTC
    EVA #1: 7 hours, 11 minutes
    EVA #2: 7 hours, 23 minutes
    EVA #3: 5 hours, 40 minutes
    Liftoff: 24 April 01:25:48 UTC

Landing:
    Location: Pacific Ocean (0° 43' S, 156° 13' W)
    Vessel: USS Ticonderoga (CVS-14)
    Date: 27 April 1972
    Time: 19:45:05 UTC

Mission Duration: 11 days, 1 hour, 51 minutes, 5 seconds
Surface Stay Time: 2 days, 23 hours, 2 minutes, 13 seconds

Time in lunar orbit: 126 hours, with 64 orbits. 213 lbs of material gathered. Lunar Rover used for second time. Young and Duke performed 3 EVA's lasting 20 hours, 14 minutes. Mattingly performed a trans-Earth EVA to retrieve film.

The Command and Service Module (CSM) was named Casper, and the Lunar Module (LM) was named Orion.

The lunar landing location was not changed as a result of Apollo 13.

The Apollo 16 command module is on display at the U.S. Space and Rocket Center, Huntsville, AL.